Name：Regorafenib

Introduction

It inhibits PDGFR tyrosine kinase with IC50=83nM. It is useful for the treatment of inflammation and as an anti-proliferative agent.

General information

Regorafenib

By name:

4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]-3-fluorophenoxy]-N-methylpyridine-2-carboxamide; 4-[4-({[4-Chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)-3-fluorophenoxy]-N-methylpyridine-2-carboxamide; 4-(4-(3-(4-Chloro-3-(trifluoromethyl)phenyl)ureido)-3-fluorophenoxy)-N-methylpicolinamide; Stivarga®; BAY 73-4506;

CAS no：755037-03-7

Molecular formula：C21H15ClF4N4O3

Molecular weight：482.81500

PSA：92.35000

LogP：6.22570

Boiling point：513.4?C at 760 mmHg

Flashing point：264.3?C