Description:
Name:Cetilistat
Appearance: Off-white cryst.
CAS No.:282526-98-1
Density: 1.027 g/cm3
Formula: C25H39NO3
Boiling Point: 509.671 °C at 760 mmHg
Molecular Weight: 401.58
Flash Point: 158.925 °C
Synonyms: 2-(Hexadecyloxy)-6-methyl-4H-3,1-benzoxazin-4-one;
执行标准(Perform standard):企业标准(Enterprise Standard) |
|
分析项目 ITEM OF ANALYSIS |
指标 STANDARD |
性状Appearance |
白色至棕色粉末 White to brown powder |
鉴别 Identification |
应符合规定 Conforms |
水分water |
≤0.5% |
残留溶剂 Solvent residue |
丙酮Acetone ≤5000ppm |
乙腈Acetonitrile≤410ppm |
|
重金属Heavy metals |
≤20ppm |
纯度HPLC |
≥99.0% |
单一杂质Single impurity |
≤0.2% |
炽灼残渣Residue on Ignition |
≤0.2% |
结论Conclusion |
符合企业标准Conforms to Enterprise Standard |
The Cetilistat is an organic compound with the formula C25H39NO3. The IUPAC name of this chemical is 2-hexadecoxy-6-methyl-3,1-benzoxazin-4-one. With the CAS registry number 282526-98-1, it is also named as 4H-3,1-benzoxazin-4-one, 2-(hexadecyloxy)-6-methyl-. The product's classification code is Treatment of obesity. Besides, it is a drug designed to treat obesity. It acts in the same way as the older drug orlistat by inhibiting pancreatic lipase, an enzyme that breaks down triglycerides in the intestine. Without this enzyme, triglycerides from the diet are prevented from being hydrolyzed into absorbable free fatty acids and are excreted undigested.
Function:
Cetilistat is a drug designed to treat obesity. It acts in the same way as the older drug orlistat(Xenical) by inhibiting pancreatic lipase, an enzyme that breaks down triglycerides in the intestine. Without this enzyme, triglycerides from the diet are prevented from being hydrolyzed into absorbable free fatty acids and are excreted undigested.
Application:
In human trials, cetilistat was shown to produce similar weight loss to orlistat, but also produced similar side effects such as oily, loose stools, fecal incontinence, frequent bowel movements, andflatulence.It is likely that the same precautions would apply in that absorption of fat-soluble vitamins and other fat-soluble nutrients may be inhibited, requiring vitamin supplements to be used to avoid deficiencies
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