乙磺酸尼达尼布
英文名称:Nintedanib esylate
中文名称:乙磺酸尼达尼布 中文别名:尼达尼布乙磺酸盐; (3Z)-2,3-二氢-3-[[[4-[甲基[2-(4-甲基-1-哌嗪基)乙酰]氨基]苯基]氨基]苯亚甲基]-2-氧代-1H-吲哚-6-甲酸甲酯乙磺酸盐;
英文名称:Nintedanib esylate
英文别名:
(3S,5S)-3,5-Bis[[(1,1-dimethylethyl)dimethylsilyl]oxy]-1-hydroxy-cyclohexanecarboxylic Acid Methyl Ester;
3-Z-[1-(4-(N-((4-methyl-piperazin-1-yl)-methylcarbonyl)-N-methyl-amino)-anilino)-1-phenyl-methylene]-6-methoxycarbonyl-2-indolinone monoethanesulphonate;
3-Z-[1-(4-(N-((4-methyl-piperazin-1-yl)-methylcarbonyl)-N-methyl-amino)-anilino)-1-phenyl-methylene]-6-methoxycarbonyl-2-indolinone monoethanesulfonate;
Methyl (3Z)-3-[({4-[N-methyl-2-(4-methylpiperazin-1-yl)acetamido]phenyl}
amino)(phenyl)methylidene]-2-oxo-2,3-dihydro-1H-indole-6-carboxylate ethanesulfonate salt;
3-Z-[1-(4-(N-((4-methyl-piperazin-1-yl)-methylcarbonyl)-N-methyl-amino)-anilino)-1-phenyl-methylene]-6-methoxycarbonyl-2-indolinone monoethanesulfonate salt;
CAS号:656247-18-6
分子式:C33H39N5O7S
分子量:649.75700
精确质量:649.25700
PSA:160.46000
LogP:4.62470
分析项目 ITEM OF ANALYSIS |
指标 STANDARD |
外观 Appearance |
浅黄色到黄色粉末 Light yellow to yellow powder |
鉴别 Identification |
符合LC-MS检测 Conforms LC-MS test |
符合1HNMR检测 Conforms 1HNMR test |
|
单一杂质 Individual impurity |
≤0.50% |
水分 Water |
≤0.50% |
纯度 Purity |
≥99.0% |
结论 Conclusion |
符合企业标准 Conform with in-house Specification. |
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