欢迎光临~山东海沃生物科技有限公司
语言选择: 中文版 ∷  英文版

他达那非

  • 他达那非 CAS No. 171596-29-5
  • 他达那非 CAS No. 171596-29-5
  • 他达那非 CAS No. 171596-29-5
他达那非 CAS No. 171596-29-5他达那非 CAS No. 171596-29-5他达那非 CAS No. 171596-29-5

他达那非 CAS No. 171596-29-5

  • EP/USP standard
  • 包装规格:1kg/25kg/按照客户要求
  • 生产能力:1~2吨/月
  • 库存:长期大量库存
  • 产品描述:他达拉非,tadalafil ,171596-29-5
  • 在线订购

基本信息

中文名称:他达那非

中文别名:西力士;他地那非;

英文名称:Tildenafil

英文别名:Cialis;

(6R,12aR)-6-(benzo[d][1,3]dioxol-5-yl)-2-methyl-2,3,12,12a tetrahydropyrazino [1',2':1,6] pyrido[3,4b] indole1,4(6H,7H)-dione;

(6R,12aR)-6-(1,3-benzodioxol-5-yl)-2-methyl-2,3,6,7,12,12a-hexahydropyrazino[1',2':1,6] pyrido[3,4-b]indole-1,4-dione;

CAS号:171596-29-5

分子式:C22H19N3O4

分子量:389.40400

精确质量:389.13800

PSA74.87000

LogP2.08710

物化性质

外观与性状:白色或类白色粉末

密度:1.51 g/cm3

熔点:298-300?C

沸点:679.1?C at 760 mmHg

闪点:364.5?C

折射率:1.705

蒸汽压:5.29E-13mmHg at 25°C

分析项目

ITEM OF ANALYSIS

标准

STANDARD

性状Appearance

白色或类白色粉末White or almost white crystalline powder

溶解度

Solubility

几乎不溶于水,易溶于二甲亚砜,微溶于二氯甲烷

Practically insoluble in water, freely soluble in dimethyl sulfoxide, slightly soluble in methylene chloride

熔点

Melting point

302~303

鉴别

Identification

红外图谱与参照图谱一致

The infrared absorption spectrum is concordant with the reference spectrum

供试品溶液中主峰的保留时间应与鉴别溶液中主峰的保留时间一致

The principal peak in the chromatogram obtained with the test solution is similar in retention time and size to the principal peak in the chromatogram obtained with reference solution

比旋度

Rotation

+ 78.0°to + 84.0°

杂质A,B,C

Impurities A, B and C

杂质 A, B and C0.1%

Impurity  A, B and C0.1%

干燥失重

Loss on drying

0.5%

炽灼残渣

Residue on ignition

0.1%

重金属

Heavy metals

10ppm


有关物质(HPLC

Related substances

单项杂质≤0.1%

Individual impurity0.1%

总杂质≤0.3%

Total unknown impurity0.3%

残留溶剂

Residual Solvents

甲醇≤0.3%

Methanol;0.3%

乙酸乙酯≤0.5%

EA0.5%

异丙醇≤0.5%

IPA0.5%

乙酸甲酯≤0.5%

Methyl acetate0.5%

二氯甲烷≤0.06%

DCM0.06%

醋酸≤0.5%

AceticAcid0.5%

含量Assay

98% ~ 102.0 % (干品计dried substance).

结论

Conclusion

本品按EP 9/USP40标准检验,结果符合规定。

The test results conform with EP 9/USP40 Specification.